Nationwide Children Kidney and Urinary Tract Symposium State of the Art in Pediatric UTI 2025

Date & Location: Thursday, February 20, 2025, 4:00 PM – Friday, February 21, 2025, 4:30 PM, Nationwide Children’s Hospital Conference Center, COLUMBUS, OH, OH
Target Audience: Specialties – General Pediatrics, Infectious Diseases, Nephrology, Urology

Overview
The overall goal of this fourth annual symposium is to provide a current, high-level summary of the state-of-the-art regarding mechanisms and management of pediatric UTI. A panel of experts will highlight knowledge gaps and making recommendations about next steps for research to guide the care of patients with UTI. This includes the role for host-pathogen interactions in UTI pathogenesis; host defense mechanisms to prevent and eradicate UTI; urologic evaluation of patients with recurrent UTI; antibiotic prophylaxis in UTI prevention; and the impact of recurrent UTI on the kidney. Facilitated discussions will provide opportunities to gather patient and caregiver perspectives and identify research opportunities and priorities, to achieve the best future for children with UTI.
Objectives
At the conclusion of this activity, learners will be able to:

Describe mechanisms of urinary tract infection (UTI) pathogenesis
Utilize emerging measures to prevent and treat UTI
Implement the latest clinical approaches to UTI diagnosis, treatment and prevention
Reduce the impact of UTI on patients and caregivers by implementing new strategies.
Improve communication and collaboration with the healthcare team.

 
+ Topics:
*Note: these are continuous video recordings during the conference, they include individual lectures mentioned in the Detail section below
Feb 21.mp4 (8 hours)
Antibiotic Prophylaxis for UTI.pdf
Innate defenses in UTI- Interleukin-6 impacts urothelial immunity.pdf
Understanding UTIs Immune Mechanisms, Models, and Therapies Across the Lifespan.pdf
UTI and Epithelial Immunity.pdf
UTI Pathogens, Epidemiology, and Resistance.pdf
Why Do We Care About UTI.pdf
 
* Detail:
Friday, February 21, 2025

Welcome and Introductions
8:15AM – 8:30AM

Why Do We Care About UTI
8:30AM – 9:15AM
Nader Shaikh, MD, MPH

UTI Pathogens, Epidemiology, and Resistance
9:15AM – 10:00AM
Laura A Mike, PhD

A Mouse Model of Acquired Renal Scarring after UTI
10:00AM – 10:15AM
Denise Kimbrough, MD PhD

Break
10:15AM – 10:30AM

Understanding UTIs: Immune Mechanisms, Models, and Therapies Across the Lifespan
10:30AM – 11:15AM
Indira Mysorekar, PhD, FAAM

Antibiotic Prophylaxis for UTI
11:15AM – 12:00PM
David Hains, MD, MBA

Lunch
12:00PM – 1:00PM

Innate defenses in UTI: Interleukin-6 impacts urothelial immunity
1:00PM – 1:30PM
Christina Ching, MD

SUPER Lightning Presentations
1:30PM – 2:00PM
Characterization of UTI Defenses in Diabetic, Obese ob/ob Mice
Natalia Cuyler
Point Reyes, CAEnhancing Antimicrobial Functions in Neutrophils to Combat Urinary Tract Infections
Josh Putka
Avon, OH
Impact of Uropathogenic Escherichia coli on the mTOR Signaling Pathway
Vanessa Arias
Garfield, NJ

UTI Treatment and NCH UTI Pathway
2:00PM – 2:30PM
Joshua Watson, MD

Break
2:30PM – 2:44PM

Urologic Evaluation of rUTI
2:45PM – 3:30PM
Luis Braga, MD, MSc, PhD

Unveiling Biomarkers and Mechanistic Pathways in Acute Pyelonephritis Through a Spatio-Temporal Transcriptome Atlas
3:30PM – 4:00PM
Juan de Dios Ruiz Rosado, PhD