By David W. Kang, Renee Tannenbaum ‘ENHANZE® drug delivery technology: Advancing subcutaneous drug delivery using recombinant human hyaluronidase PH20’ provides readers with in-depth information on the potential benefits and challenges of subcutaneous (SC) drug delivery, the biology of hyaluronan and hyaluronidases in the SC space, and a comprehensive overview on the history of hyaluronidases and the development of recombinant human hyaluronidase PH20 (rHuPH20). Current applications of rHuPH20 as well as approved biotherapeutics utilizing HuPH20-facilitated SC drug delivery are summarized, and the underlying non-clinical and clinical development approaches are introduced as a basis for future application to biologics in various disease areas.
Product Details
ASIN : B0B57JMGDJ
Publisher : S. Karger; 1st edition (June 14, 2022)
Publication date : June 14, 2022
Language : English
Screen Reader : Supported
Page numbers source ISBN : 3318070769
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