INBBC 2025 16th International Newborn Brain Conference
February 19th – 21st, 2025
La Jolla, San Diego – California
The International Newborn Brain Conference (INBBC) provides a state-of-the-art forum for presentation and discussion of current research and clinical practice in newborn brain care, including diagnosis, monitoring and management strategies to optimize neurodevelopmental outcome. It explores the means to understand, monitor, protect and treat the newborn brain. The INBBC provides continuing medical education to multidisciplinary professionals working to improve the neurological and developmental health outcomes of premature and high-risk newborns.
Main Topics
Fetal Neuroprotection
Parent Counselling
Artificial Intelligence in Neurocritical Care
Neuroimaging
Neonatal Seizures
Neuromonitoring
Neuromuscular Diseases
Quality Improvement
Neuroplasticity and Rehabilitation
Hot Topics in Neonatal Neurology
Scientific Programme
Wednesday, February 19
Thursday, February 20
Friday, February 21
07:00 – 08:30
07:00 – 08:00
07:00 – 08:00
Registration opens (workshop only)
Registration open
Registration open
Regency Foyer C
Regency Foyer C
Breakfast
07:00 – 08:30
07:00 – 08:00
SHOR
Breakfast (served for Workshop participants only)
Breakfast
08:00 – 09:30
La Jolla Ballroom
La Jolla Ballroom
Platform Session 4: Neonatal Seizures: From basic science to new therapies
*The Terrace
*La Jolla Garden
Moderators: Adam Numis, Lena Hellstrom Westas
*La Jolla Garden
07:00 – 08:00
08:00 – 08:30
08:30 – 10:00
NBS-TEC Breakfast Mixer (RSVP only)
Basic Science of Seizure Mechanisms and Harm of Seizures
Workshops A
The Terrace
Speaker: Kevin J. Staley
7 parallel workshops (5 in-person, 2 online)
08:00 – 08:30
08:30 – 09:00
08:30 – 10:00
Platform Session 2: AI in Neonatal Neurocritical Care
Seizure Burden – How Best to Measure
CUS – Hands on Simulation
Moderators : Gabriel Variane, Janet Soul
Speaker: Courtney Wusthoff
Speakers: Khorshid Mohammed, Sylke Steggerde, Lara Leijser
08:00 – 08:30
09:00 – 09:30
Encinitas room
AI and Big Data in Neonatal Neurocritical Care
Current and Future Medications for Neonatal Seizures: Challenges and Opportunities
08:30 – 10:00
Speaker: Alvaro Moreira
Janet Soul
Basics of Quality Improvement Part A
08:30 – 09:00
09:30 – 10:15
Speakers: Jehier Afifi, Bharati Sinha, Tetyana Nesterenko
AI and Neurophysiology
Coffee Break (AM)
Del Mar room
Speaker: Sampsa Vanhatalo
Regency Foyer C
08:30 – 10:00
09:00 – 09:30
10:15 – 11:45
Common Fetal Consults
AI and Neuroimaging in Neurocritical Care
Abstract platform presentations 2
Speakers: Janet Soul, Sarah Mulkey
Speaker: Ellen Grant
Moderators: Pia Wintermark, Christopher Elitt
Regency AB
09:30 – 10:15
1. Neurodevelopmental outcomes of normocephalic Colombian children with antenatal Zika virus exposure at school age
08:30 – 10:00
Coffee Break (AM)
Sarah Mulkey
Neuroimaging in Term Neonates
Regency Foyer C
2. Dysregulated Fatty Acid Metabolism Following Neonatal Brain Injury is Rescued by Treatment with Acetate
Speakers: Linda de Vries, Sonia Bonifacio
10:15 – 11:45
Joseph Scafidi
Solana Beach room
Platform Session 3: Rare Neuromuscular Disorders: Emerging Gene/Precision Therapies
3. Telehealth Hammersmith Infant Neurologic Exam supports early diagnosis of cerebral palsy
08:30 – 10:00
Moderators: Betsy Ostrander, Ulrike Mietzsch
Jennifer Keene
NIRS Basics and Clinical Applications
10:15 – 10:45
4. Assessing Neonatal Brain Glymphatic System Development Using DTI-ALPS and Choroid Plexus Volume
Speakers: Valerie Chock, Mohamed El-Dib
Metabolic Myopathies in Newborns
Ting Peng
Regency C
Speaker: Walla Al-Hertani
5. Automated EEG background in a multicenter cohort of neonates with hypoxic-ischemic encephalopathy and neurodevelopmental outcomes.
08:30 – 10:00
10:45 – 11:15
Marie Cornet
Neuroimaging in Preterm
Spinal Muscular Atrophy
6. Perinatal Arterial Stroke treated with Stromal cells IntraNasally (PASSIoN) trial: two-year safety and neurodevelopmental outcome
Speakers: Terrie Inder, Christopher Smyser
Speaker: Perry Shieh
Lisanne M. Baak
Boardroom
11:15 – 11:45
7. MRI Score and EEG for Two-Year Outcome Prediction: A Secondary Analysis of the ANSeR Studies
08:30 – 10:00
Neonatal-onset Myopathies and Dystrophies
Anne Murray
aEEG & cEEG Basics
Speaker: Carsten G. Bönnemann
8. Early Machine-Learning Based Quantitative EEG Correlates to Extent of MRI Brain Injury in Neonatal Encephalopathy
Speakers: Geraldine Boylan, Lena Hellstrom-Westas
11:45 – 13:30
Huzaifah Shamim
Cardiff
Lunch
9. Reduced Amygdala Volumes at 6-8 Years in Children Cooled for HIE: Associations With Socioemotional Outcomes
10:00 – 10:30
(At leisure, not provided by the conference)
Sara Rapuc
Coffee Break (AM Break)
12:00 – 13:20
11:45 – 13:30
Regency Foyer C
Building long-term follow-up guidelines for HIE: A multidisciplinary workshop hosted by Hope for HIE (RSVP only)
Lunch
10:30 – 12:00
La Jolla Ballroom
(At leisure, not provided by the conference)
Workshops B
13:30 – 15:00
13:30 – 15:00
7 parallel workshops (5 in-person, 2 online)
Abstract platform presentations 1
Hot Topic Symposia
10:30 – 12:00
Moderators: Diane Wilson, Hannah Glass
Moderators: Emily Herzberg, John Barks
CUS – Hands on Simulation
1. Sleep-Disordered Breathing Among Newborns with Fetal vs. Postnatal Myelomeningocele Closure
13:30 – 14:00
Speakers: Khorshid Mohammed, Sylke Steggerde, Lara Leijser
John Barks
WES and WGS in Neonates
Encinitas room
2. Temporal Analysis of Neonatal SpO2 Patterns Using AI Reveals Early Predictive Signatures of Severe IVH
Speaker: Pankaj Agrawal
10:30 – 12:00
Zachary Vesoulis
14:00 – 14:30
Basics of Quality Improvement Part B
3. Association between trajectories of autonomic cardiorespiratory maturation and brain volumetric growth in preterm infants
Fetal Diagnosis and Intervention for Vascular Malformations
Speakers: Jehier Afifi, Bharati Sinha, Tetyana Nesterenko
Julius Ngwa
Speaker: Darren Orbach
Del Mar room
4. Neonatal sleep physiology and early executive functioning in children born preterm
14:30 – 15:00
10:30 – 12:00
Anneleen Dereymaeker
Novel Fetal Neuroimaging and Therapies
Straight talk: hard conversations in the NICU
5. Predicting neurodevelopmental outcomes in infants with spina bifida myelomeningocele
Speaker: Ellen Grant
Speakers: Lauren Treat, Betsy Pilon
Pei-Yi Lin
15:00 – 15:45
Ocean Beach 1&2
6. Maternal immune activation and hypoxia induce neuronal mitochondrial injury preventing cell-cycle exit, arresting cerebellar development
Coffee Break (PM)
10:30 – 12:00
Gabriele Simonti
Regency Foyer C
Neuroimaging in Term Neonates
7. The NutriBrain trial: Can probiotics, prebiotics and glutamine support white matter development in preterm infants?
15:45 – 17:15
Speakers: Linda de Vries, Sonia Bonifacio
Els Janson
Platform Session 5: Rehabilitation for Children with or at Risk for Hemiparetic CP
Boardroom
8. Melatonin as a neuroprotective strategy in preterm infants: antioxidant properties, neurological outcomes and MRI findings
Moderators: Alexandra Santana Almansa, Santina Zanelli
10:30 – 12:00
Cecilia Naboni
15:45 – 16:15
NIRS Basics and Clinical Applications
9. Blood-brain barrier disruption and fibrinogen deposition in the embryonic brain after maternal immune activation
Early Diagnosis of Cerebral Palsy
Speakers: Valerie Chock, Mohamed El-Dib
Martin Grana
Speaker: Betsy Ostrander
Cardiff
15:00 – 15:45
16:15 – 16:45
10:30 – 12:00
Coffee Break (PM)
Principles of Rehabilitation After Neonatal Brain Injury/Constraint and Other Infant Rehab Therapies
Neuroimaging in Preterm
Regency Foyer C
Speaker: Iona Novak
Speakers: Terrie Inder, Christopher Smyser
15:45 – 16:45
16:45 – 17:15
Regency C
Small Group Discussions 1
Brain computer interfaces to enable life participation for children after perinatal brain injury.
10:30 – 12:00
15:45 – 16:45
Speaker: Adam Kirton
EEG and Seizures – Clinical Videos & Practical Treatment
Developmental Care During TH
17:15 – 17:30
Speakers: Janet Soul, Courtney Wusthoff
Speakers: Diane Wilson, Mary Anne Ryan
Closing Remarks
Regency AB
Regency AB
12:00 – 13:45
15:45 – 16:45
Lunch Break
IVH & PHH Prevention and Management
(At leisure, not provided by the conference)
Speakers: Mohamed El Dib, Linda de Vries
13:45 – 14:00
Cardiff
Opening Remarks
15:45 – 16:45
14:00 – 15:30
Management During HIE
Platform Session 1: Fetal Neuroprotection: Understanding Pathophysiology, Risk Factors and Antenatal Therapies
Speakers: Sonia Bonifacio, Hannah Glass
Moderators: Sarah Mulkey, Bharati Sinha
Solana Beach room
14:00 – 14:30
15:45 – 16:45
Neuroplacentology
Neonatal Neurocritical Care Training
Speaker: Anna Penn
Speakers: Khorshid Mohammad, Chris Smyser
14:30 – 15:00
Boardroom
Chorioamnionitis – Animal Models –
15:45 – 16:45
Speaker: Henrik Hagberg
Working with Industry
15:00 – 15:30
Speakers: Geraldine Boylan, Betsy Pilon, Terrie Inder
Antenatal Neuroprotection – Steroids, Mg, etc
Regency C
Speaker: Bridget Ostrem
15:45 – 16:45
15:30 – 16:00
Connecting Families to Resources
Break
Speakers: Monica Lemmon, Lauren Treat
16:00 – 19:00
Encinitas
Reception and Poster Walk
16:45 – 17:45
La Jolla Ballroom
Small Group Discussions 2
16:45 – 17:45
Developmental Care During TH
Speakers: Diane Wilson, Mary Anne Ryan
Regency AB
16:45 – 17:45
IVH & PHH Prevention and Management
Speakers: Mohamed El Dib, Linda de Vries
Regency C
16:45 – 17:45
Management During HIE
Speakers: Sonia Bonifacio, Hannah Glass
Cardiff
16:45 – 17:45
Neonatal Neurocritical Care Training
Speakers: Khorshid Mohammad, Chris Smyser
Solana Beach room
16:45 – 17:45
Working with Industry
Speakers: Geraldine Boylan, Betsy Pilon, Terrie Inder
Boardroom
16:45 – 17:45
Connecting Families to Resources
Speakers: Monica Lemmon, Lauren Treat
Encinitas
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